troponin t การใช้

• This prognostic information was independent of troponin T, ECG and clinical examination.
• H-FABP is more effective than Troponin T in risk stratifying Chronic Heart Failure patients.
• Cardiac troponin T and I can be used to monitor drug and toxin-induced cardiomyocyte toxicity ..
• Troponin T was discovered by the German physician Hugo A . Katus at the University of Heidelberg.
• He also developed the troponin T assay.
• For example, troponin T mutations were originally associated with a 50 % mortality before the age of 40.
• Patients with end-stage renal disease can have chronically elevated troponin T levels, which are linked to a poorer prognosis.
• For example, troponin T mutations are associated with a 50 % mortality before the age of 40, while ?-myosin mutations are less threatening.
• The TNNT2 gene is located at 1q32 in the human chromosomal genome, encoding the cardiac muscle isoform of troponin T ( cTnT ).
• Troponin T binds to tropomyosin and helps position it on actin, and with the rest of the troponin complex modulates contraction of striated muscle.
• Heart muscle injury characterized by elevated levels of CK-MB, troponin I, and troponin T may occur in up to 30 % of all PCI procedures.
• Troponin I interacts with all major regulatory proteins in the sarcomeric thin filaments of cardiac and skeletal muscles : troponin C, troponin T, tropomyosin and actin.
• Alongside D-dimer, NT-proBNP and peak troponin T, it was the only cardiac biomarker that proved to be a statistically significant predictor of death or MI at one year.
• A study at the Swedish Karolinska Institute, not yet formally reported in a journal, showed that high-sensitivity cardiac troponin T did have some predictive power in telling which patients with chest pain would be at risk.
• In cardiac muscle, cTnC binds to cardiac troponin I ( cTnI ) and cardiac troponin T ( cTnT ), whereas cTnC binds to slow skeletal troponin I ( ssTnI ) and troponin T ( ssTnT ) in slow-twitch skeletal muscle.
• The study on troponin T, led by cardiologist Dr . Magnus Ohman of the Duke Clinical Research Institute, found a comparable result _ higher levels of the proteins indicated patients were three times as likely to die within a month.
• In cardiac muscle, cTnC binds to cardiac troponin I ( cTnI ) and cardiac troponin T ( cTnT ), whereas cTnC binds to slow skeletal troponin I ( ssTnI ) and troponin T ( ssTnT ) in slow-twitch skeletal muscle.
• Writing in Thursday's New England Journal of Medicine, two teams who studied nearly 2, 300 patients describe the predictive benefits of tests for troponin I and troponin T . These proteins are found in the blood only after damage to heart tissue has occurred.
• In patients with stable coronary artery disease, troponin T concentrations have long been found to be significantly associated with the incidence of cardiovascular death and heart failure, but it was 2014 before it began to be accepted in predicting who would later suffer acute myocardial infarction ( heart attack ).
• Three homologous genes have evolved in vertebrates, encoding three muscle type-specific isoforms of TnI . Sequence analysis, immunological distance, and examination of evolutionarily suppressed conformational states showed that the TnI genes have evolved in close linkage with the genes encoding troponin T ( TnT ), another subunit of the troponin complex.